CURRICULUM VITAE
NAME: Hak-Kim Chan, BPharm, PhD
Professor in Pharmaceutics (Advanced Drug Delivery)
ADDRESS: (Work) Faculty of Pharmacy
University of Sydney
NSW 2006, Australia.
Phone (02) 9351-3054 Fax (02) 9351-4391
Email: kimc@pharm.usyd.edu.au
EDUCATION and AWARDS:
2006 Fellow of the American Association of Pharmaceutical
Scientists
2005 Grand Prize of Innovation Challenge, University of Sydney
2004 Faculty of Pharmacy Excellence in Teaching Award for
Physical Pharmaceutics and Formulation, University of Sydney
1999 Awarded the John A Brodie Medal by the Institute of
Engineers Australia for achievement on processing of
pharmaceutical powders for aerosol applications.
1998 Graduate Certificate in Educational Studies (Higher Education)
University of Sydney
1989 Awarded the Sigma Drug Delivery Prize 1989 Australia for
research on cromoglycic acid powder for inhalation.
Jun 1988 PhD in Pharmaceutics, University of Sydney.
1984 - 1988 Research on "Crystal Growth and Aerodynamics of Drug
Particles" leading to a PhD degree in pharmaceutics in the
Faculty of Pharmacy, University of Sydney, NSW, Australia.
Mar 1984 Awarded U.R.G. special project grant overseas scholarship by
the University of Sydney for four years.
Aug 1983 Graduated BPharm. Ranked the first in a class of twenty-two.
1979 - 1983 Awarded 5 prizes and 1 medal for distinction in academic
record. School of Pharmacy, National Defense Medical Center,
Taipei.
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EMPLOYMENT HISTORY
Jan 2007 – present Professor, Faculty of Pharmacy, University of Sydney.
Jan 2002 – Dec 2006 Associate Professor, Faculty of Pharmacy, University of
Sydney.
Jan 2002 – Dec 2002 Acting Head of Pharmaceutics, Faculty of Pharmacy,
University of Sydney.
Jan 1999 – Dec 2001 Senior Lecturer, Faculty of Pharmacy, University of Sydney.
Aug 1995 – Dec 1998 Lecturer, Department of Pharmacy, University of Sydney
May 1992 - Aug 1995 Scientist, Department Pharm R & D, Genentech, Inc., South
San Francisco.
Jul 1989 - Dec 1991 Postdoctoral fellow, Faculty of Pharmacy, University of
Sydney.
Jul 88 - Jun 89 Postdoctoral associate, College of Pharmacy, University of
Minnesota, Minneapolis, USA.
TEACHING EXPERIENCE:
Lecturing on formulation and physical pharmaceutics (1995-
present). Coordinator of third year Formulation course (2003-
2006). Coordinator of second year Physical Pharmaceutics
course (1995-2002). Coordinator of third year dispensing
course (1995). (Detailed in Attachments 1 to 4)
ADMINISTRATIVE
EXPERIENCE: Besides the regular teaching administration (Detailed in
Attachments 1 & 2) and Faculty administration (Attachment 9),
I have extensive administrative experience in interfacing with
the pharmaceutical industry (Attachment 6).
PROFESSIONAL
EXPERIENCE: My professional activities are detailed in Attachments 8 and 10
RESEARCH EXPERIENCE:
Therapeutic and diagnostic inhalation aerosols: in vitro
generation and characterization, including dry powder aerosols
and radioaerosols from medical jet nebulisers, and in vivo
studies of pulmonary deposition and mucociliary clearance
using single photon emission computed tomography (SPECT).
Development of stable formulations of therapeutic recombinant
human proteins. Solid and solution state characterization of
proteins.
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Particle engineering of drugs, and their characterization,
including the mechanisms of crystal growth and shape
modifications of pharmaceutical particles. Effects of crystal
defects and impurities on the dissolution rate and other crystal
properties of drug and excipients.
RESEARCH INTERESTS:
Formulation and delivery of therapeutic and diagnostic aerosols
for inhalation. In vivo deposition and clearance studies by
gamma scintigraphy.
Biotechnology-derived protein pharmaceuticals development -
formulation and aerosol delivery.
Application of novel powder technology and particle
engineering of pharmaceuticals to drug delivery systems and
dosage form design, i.e. the modification of physical form,
dissolution rate, physical properties, mechanical behaviour and
formulation characteristics of pharmaceutical solids by
processing treatment e.g. supercritical fluid technology
PUBLICATIONS: A complete list is attached separately.
PATENTS Six patents on pharmaceutical formulations including
biotechnology proteins (Detailed in the Application)
INVITED TALKS: Invited keynote speaker in various scientific conferences,
academic institutes and industry (Detailed in Attachment 7)
JOURNAL EDITORIAL International Journal of Pharmaceutics
BOARD MEMBER Pharmaceutical Research
Current Clinical Pharmacology
Recent patents in Biotechnology
Recent patents in Drug Delivery and Formulations
Pharmaceutical technology Asia
Hong Kong Pharmaceutical Journal
PROFESSIONAL Royal Australian Chemical Society (2005-present)
MEMBERSHIP: International Society for Aerosols in Medicine (1993-2005)
American Association of Pharm Scientists (1995-present)
Australasian Pharmaceutical Science Association (1995-2000)
Sigma Xi (1992-1997)
New York Academy of Science (1992-1996)
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